Electrochemical Sensor Chip

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Introduction of Electrochemical Sensor Chip

The electrochemical sensor is based on the electrochemical properties of the analyte and converts the chemical quantity into an electrical quantity for sensing detection. In recent years, the electrochemical sensor has been widely used in many branches of environment, traffic, industry, and medical monitoring. As a well-established and powerful tool, real-time information can be obtained via chemical composition measurement without sampling. The characterizations of sensors, including sensitivity, selectivity, and stability, are mainly determined by the measuring conditions respecting pressure, temperature, and chemical environment. Depending on the used electrolyte, the electrochemical sensors work at temperatures ranging from -30℃ to 1600℃.

Microfluidic-based Electrochemical Sensor Development

The microfluidic system is a process of manipulating a tiny volume of liquid in a pipe of tens to hundreds of microns. Microfluidic devices have the following advantages: small size, reduced reagent consumption, parallel detection of multiple samples, increased reliability, sensitivity, etc. In this case, the electrochemical system can be easily integrated into the microfluidic chip. Compared with traditional analysis platforms, microfluidic-based electrochemical sensors present superior sensitivity and versatility, as well as dexterous sample processing. What’s more, using micro-electrodes and nano-structured electrodes, a fast sensor response can be obtained.

Microfluidic-based Electrochemical Sensor Application

The microfluidic-based electrochemical sensors have been widely used in multiple applications, here we describe the biosensor for pathogen detection. The current methods used for bacteria detection are cultivation techniques, polymerase chain reaction (PCR), and the combined methods of these two. However, these techniques are time-consuming and expensive. In this case, with the aid of smart nanomaterials, the biosensor successfully detected pathogens in different matrices. The novel fully automated device is composed of three parts, including the integrated microfluidic system, the new biochip design, and real-time amperometric measurements. With extremely high sensitivities, this device is capable of monitoring and detecting foodborne and waterborne bacteria pathogens.

Fig. 1 Microfluidic electrochemical sensor.¹

As a leading custom service provider in the field of microfluidic chip development, Creative Biolabs has won a good reputation among our worldwide customers for successfully accomplishing numerous challenging projects including electrochemical sensor development for special functions. With years of experience and advanced platforms, we can offer one-stop microfluidic solutions to meet the special needs of our clients. If you are interested in our services, please do not hesitate to contact us for more detailed information.

Reference

Lee, Kim, et al. " Single Microfluidic Electrochemical Sensor System for Simultaneous Multi-Pulmonary Hypertension Biomarker Analyses." Scientific Reports 7 (2017): 7545.

For Research Use Only. Not For Clinical Use.