Microfluidics-Based Analysis in Medical Science
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Combining advanced micro-manufacturing concepts and biological theoretical knowledge, Creative Biolabs provides our clients with the most reliable and comprehensive one-stop microfluidic medical research solutions to help our clients reduce reagent requirements, shorten measurement time, and reduce the cost of drug development.
Microfluidic for Medical Science
Microfluidics, which deals with fluids in structures, has been widely used in the medical field and related research. The miniaturized structure promotes the mixing of the liquid phase, heat exchange and mass transfer process. The proven microfluidic dynamic theory allows high-precision flow control of the system to achieve higher reliability and sensitivity. Integrated devices endow microfluidic chips with unparalleled portability and mass production possibilities. The microfluidic system will greatly reduce the use of reagents and shorten the time of biological assay and chemical reaction, making a breakthrough in the medical field.
Early diagnosis of diseases is crucial, as it can greatly facilitate early intervention by medical staff and improve recovery rates, which will fundamentally improve or even prevent the prevalence of pathogens and infectious diseases. Traditional medical testing methods rely on complex laboratory equipment and trained operators. Labor-intensive testing techniques greatly limit the applicability and real-time performance of such tests, especially in areas with underdeveloped medical resources. The breakthrough of microfluidic biomonitoring technology provides a new option for rapid and low-cost disease monitoring in remote areas. Paper-based microfluidic chips have shown unparalleled convenience in the outbreak of large-scale infectious diseases. Various miniaturized microfluidic detection devices are also widely used in the diagnosis of infectious diseases, tumors, chronic diseases, and cardiovascular diseases.
Microfluidic technology provides a convenient tool for the development, synthesis and testing of drugs. The development and testing of new drugs is usually a cumbersome and time-consuming process. The in vitro culture model completely ignores the complex tissue environment, and the experimental results of animal models cannot be successfully and accurately translated into the results of clinical trials. In addition, the toxicity, safety, and pharmacokinetic properties of drug combinations also require a lot of reagents and time costs. Microfluidic technology realizes the spatiotemporal control of drug concentration as well as the rapid, high-throughput screening of drugs. On the other hand, the integration of various types of cells (usually of human origin) into microfluidic devices reconstructs the tissue structure and functional state in a three-dimensional environment and reproduces organ functions.
Fig. 1 Body-on-chip system are commonly used for medical sciences.1
Precision medicine represents a new and modern medical model. Precision medicine challenges the dogma of traditional one-size-fits-all diagnosis and develops toward more predictive, preventive, personalized and participatory disease intervention. The dynamic nature of organ-on-a-chip enables the development of research tools for precision medicine, where cell culture parameters and health data can be changed in a controlled manner over time. Disease progression, environmental influences, and drug effects will be systematically assessed to predict possible responses in humans, which is a subversive and breakthrough development for traditional cancer intervention methods.
Creative Biolabs is equipped with complete micro-manufacturing equipment and well-trained engineers to provide our clients with comprehensive microfluidic medical detection chip development and fabrication services. You may directly select between the functionalized chip or organ chip that suits your requirements and research project. These well-characterized devices will advance your experimental progress greatly. In addition, we are capable of developing microfluidic systems with specific functions or suitable for special scenarios under your entrustment, bringing your design into reality. Our help will assist you to maximize the benefits of this revolutionary new tool in medical diagnostics and further advance your research, so don't hesitate to contact us for more information.
Reference
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Perastrelo, Aguas, et al. " Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering." Sensors 15.12 (2015): 31142-31170.
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