Microfluidic Development Services for Droplet Generator and Flow Chemistry

Inquiry

At Creative Biolabs, we are committed to providing our customers with the most comprehensive and profitable microfluidic chip design and development services. Benefiting from the multi-faceted advantages of interdisciplinary research technologies, microfluidic droplet generators, and flow chemistry will have a wide range of potential applications.

Lab-on-Chip System

Various standard experiments in traditional biology/chemistry laboratories often require bulky and expensive equipment with a large number of experimental consumables. Our microfluidic technology platform combines precision processing and advanced knowledge from the fields of biology and chemistry, and is expected to complete these tedious laboratory procedures at one time on cheap and easy-to-obtain microchips, which will fundamentally change the tradition of the experimental pattern. The most attractive feature of microchip devices is that they replicate and miniaturize traditional experiments while greatly reducing the number of samples/reagents used while maintaining faster response times and higher sensitivity. After years of development, microfluidics has been applied in many important fields, including DNA analysis, molecular diagnosis, environmental monitoring, chemical synthesis, organ chip, cell biology, etc. Our microfluidic chips will give you the opportunity to perform completely new types of experiments and develop new chemical entities, especially in the fields of droplet generation and flow chemistry.

Fig. 1 Microfluidic technology can complete tedious experimental procedures while miniaturizing traditional experimental facilities.

Droplet Generator

Droplet generates microfluidic systems based on immiscible phase manipulation have been widely used. Through different microchannel structure designs and hydrophilic/hydrophobic transfer, the generation and manipulation of discrete volume fluids can be achieved. The simplest droplet generation device can be constructed by a simple T-Junction or flow-focusing-Junction. This type of chip stably and rapidly produces monodisperse oil-in-water or water-in-oil droplets. These fabricated uniform droplets serve as stable microreactors in biological or chemical reactions to achieve controllable, reproducible, and predictable outcomes.

Fig. 2 Microfluidic droplet generation chip can realize precise control of various parameters.¹

Droplets with more complex structures and functions can also be produced through external forces, repeating structures, or channel modification. Microgel particles with different functions will be used as new smart materials in different fields. Our droplet microfluidics technology will allow you to explore more applications including drug delivery, bioimaging, particle synthesis, cell encapsulation, chemical synthesis, drug diagnostics, DNA analysis, and many more.

Fig. 3 Schematic of microfluidic droplet generation methods.²

Continuous Flow Chemistry

Flow chemistry and related manufacturing processes offer a superior alternative to traditional batch chemistry with much more possible. Combining the theory of green chemistry and continuous flow chemistry, Creative Biolabs provides you with an automated flow chemistry synthesis platform with higher security, repeatability, and scalability. These platforms will greatly reduce costs and provide researchers in various fields with new chemical possibilities that batch chemistry cannot achieve. We will design, optimize and process various continuous-flow chemical systems to help you achieve high-precision fluid control with faster and smarter sample processing. Our continuous flow chemical chips have a higher surface area to volume ratio, faster heat transfer and mass transfer coefficients with better building flexibility, and will be your best choice for chemical synthesis, chemical processing, chemical analysis, or multi-step synthesis new tools.

Fig. 4 Microfluidic flow chemistry.³

Our Service

Creative Biolabs is keen to develop microfluidic systems with good stability, and to customize microfluidic systems for more researchers from different disciplines, so that more material processing, chemical synthesis, and biological experiment processes can benefit from it. Our services include but not limited to:

Don't hesitate to contact us for any needs.

References

Trossbach, Sanz, et al. " A Portable, Negative-Pressure Actuated, Dynamically Tunable Microfluidic Droplet Generator." Micromachines 13.11 (2022): 1823.
Lashkaripour, Mclntyre, et al. " Design automation of microfluidic single and double emulsion droplets with machine learning." Nature Communications 15 (2024): 83.
Earley, Guillou, et al. " Microfluidic Preparation of 89Zr-Radiolabelled Proteins by Flow Photochemistry." Nature Communications 15 (2024): 83.

For Research Use Only. Not For Clinical Use.