Microfluidics-based Single Emulsion Synthesis Services

Creative Biolabs introduces a single-emulsion synthesis service based on cutting-edge microfluidic technology. By leveraging precisely engineered microfluidic chip dimensions, we achieve precise control over fluid flow in laminar conditions, generating highly uniform, structurally controllable, and exceptionally stable single-emulsion droplets.

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Fig. 1 Simplified microfluidic system. (Wei, et al., 2005)

The ability to precisely achieve the required droplet size and uniformity in emulsion synthesis directly affects the performance and stability of emulsions, and is also a key criterion for assessing mass production feasibility. Our technologies enable the accurate preparation of various emulsions you need. Creative Biolabs can provide professional solutions to help you precisely synthesize the required emulsions and achieve large-scale production.

Service Portfolio

Our single emulsion synthesis services encompass a full spectrum of capabilities designed to meet the unique demands of each project.

Custom Formulation Development

We control emulsion viscosity, enhance its stability, and optimize its biocompatibility through the careful selection of surfactants, oil phases, aqueous phases, and additives. Backed by specialized screening technologies, we can efficiently test hundreds of different formulation combinations to ensure the selection of the optimal emulsion formula.

Precision Manufacturing Technologies

We are equipped with a range of cutting-edge equipment, including microfluidic technologies, membrane emulsification systems, and high-pressure homogenizers. These devices enable us to produce emulsions with excellent monodispersity and precisely control droplet sizes.

Scalability and Process Transfer

We are capable of full-scale production and can ensure completely consistent output. Our dedicated engineers conduct rigorous process validation to guarantee that emulsion droplets synthesized at different scales have the same size and quality, saving you both time and money.

Analysis and Quality Assurance

Every emulsion we produce undergoes comprehensive testing using specialized equipment to assess particle size and stability. We provide you with detailed inspection reports and stability reports for your subsequent use. To ensure that your subsequent use is not affected by changes in emulsion quality, we have also designed accelerated tests to predict long-term performance.

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Service Advantages

What sets our single emulsion synthesis services apart is a combination of technical excellence, flexibility, and client-centricity.

Advanced Technologies

We boast industry-leading microfluidic platforms and membrane emulsification technologies for emulsion homogenization, delivering results far superior to those achieved by traditional methods.

Cross-Industry Expertise

With decades of production experience, our scientists are capable of addressing the unique challenges in each field. For instance, in the pharmaceutical sector, we prioritize the biocompatibility of ingredients.

Cost-Effective Solutions

We proactively optimize formulation ratios and process flows early in the R&D phase, striving for successful emulsion synthesis on the first attempt to avoid costly rework later. Our pricing model is flexible.

Rapid Turnaround

We are equipped with modular laboratories and automated production systems. We can deliver initial prototypes in a short timeframe, saving you significant time. If you have urgent needs, feel free to choose us.

Streamlined Service Process

We've designed our workflow to be transparent, collaborative, and efficient.

Consultation and Needs Assessment

Our expert team will conduct a detailed analysis of your project goals, including the characteristics of your target emulsion and production quantification requirements. Shortly after comprehensively summarizing your various requirements, we will provide you with a project feasibility analysis and a specific design roadmap.

Formulation and Prototyping

Based on the assessment, we develop 3-5 prototype formulations for testing. Clients receive samples with comprehensive characterization data to evaluate fit-for-purpose performance.

Optimization and Scale-Up

After incorporating your feedback on the prototype design, we will refine and optimize the formulation. Once the optimal formula is confirmed with you, we will proceed to validate the production process through small-scale manufacturing to ensure consistent quality of the emulsion droplets produced and that production efficiency meets the required standards.

Production and Quality Control

We have established dedicated quality standards, which are strictly enforced throughout the entire production process. Real-time online monitoring is implemented to ensure production quality, and each batch of emulsion undergoes a final quality inspection.

Post-Delivery Support

We will provide ongoing technical support, including stability testing of emulsions. We continuously refine production protocols by adjusting formulations and optimizing processes, ensuring all your requirements are met.

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Applications Across Industries

Our single emulsion synthesis services empower innovation in diverse sectors.

Pharmaceuticals	The emulsion droplets we synthesize can be used to develop nanoemulsions for oral administration, enhancing bioavailability. For instance, poorly soluble drugs can be formulated into lipid-based preparations using our synthesized droplets to address their low solubility issues.
Cosmetics	The lightweight emulsions we produce can be used in developing skincare products such as moisturizers and sunscreens. Utilizing our synthesized emulsions helps improve the spreadability and skin permeability of skincare products.
Agrochemicals	Formulation of water-in-oil emulsions for pesticide delivery, improving efficacy and reducing environmental impact through controlled release.
Advanced Materials	We can produce emulsion microspheres for multiple applications, such as facilitating catalytic reactions, manufacturing high-sensitivity sensors, and formulating slow-release fertilizers.

Client Testimonial

"Their single emulsion synthesis service delivered exactly what we needed—consistent droplet sizes and reliable stability data. The team was responsive to our tweaks, making the process smooth from prototype to small batch."

— R&D Director, Biopharmaceutical Company

"We partnered with them for a cosmetic emulsion project. The attention to detail in testing, especially around pH and viscosity, ensured our product met specs. Delivery was on time."

— Dr. Emily Johnson, R&D Director at a pharmaceutical company.

"As a small biotech, we needed scalable nanoemulsions. Their microfluidic approach worked well, and the technical reports were clear. They adjusted the process when we scaled up, which was helpful."

— Prof. Michael Torres, Head of Biomedical Engineering Lab

"Their emulsion synthesis for our agrochemical formulation was spot-on. The controlled release profile matched our requirements, and their regulatory guidance saved us time in documentation."

— Dr. Raj Patel, Preclinical Development Lead

"We had tight deadlines for an emulsion-based sensor project. They delivered initial samples quickly, and the particle size distribution was consistent across batches. Solid communication throughout."

— Dr. Elena Kim, Principal Investigator

Published Data

A microfluidic platform for polymer synthesis cells

A study introduced a novel technique for preparing protocells using glass capillary microfluidic devices based on polymeric materials. The polymeric materials were fabricated through a surfactant-assisted dehumidification process of water-in-water (W/O/W) liquid. As shown in the figure below, the research successfully produced uniform single and double-layer polymeric structures using a dehumidification strategy based on Pluronic F-68. This represents the fastest microfluidic method for producing homogeneous polymer vesicles, offering significant advantages in minimizing exposure of encapsulated substances to organic solvents in emulsions.

Prepare double-emulsion drops in a capillary microfluidic device. (OA Literature) Fig. 1 Polymersome formation.^1,2

References

O'Callaghan, Jessica Ann, et al. "A microfluidic platform for the synthesis of polymer and polymer-protein-based protocells." The European Physical Journal E 47.6 (2024): 37. https://doi.org/10.1140/epje/s10189-024-00428-5
Distributed under Open Access license CC BY 4.0, without modification.

Created September 2025

Frequently Asked Questions

Q: Can you accommodate custom packaging or sterile requirements?

A: Yes. We offer sterile manufacturing for pharmaceutical applications and can package emulsions in vials, bottles, or bulk containers based on client needs.

Q: How long does it take to get initial emulsion samples?

A: Typically, initial samples are ready within a few weeks. It depends on formulation complexity, but we keep timelines clear from the start.

Q: Can you adjust formulations if our needs change?

A: Yes, we regularly refine formulations based on feedback. Minor tweaks are straightforward, larger changes may need extra development time.

Q: Do you provide stability testing for emulsions?

A: We include standard stability tests with all projects, covering common conditions. Additional specific tests can be arranged as needed.

Q: Is scaling up from small batches to production difficult?

A: We design processes with scaling in mind, so transitions are smooth. We work closely to ensure consistency across batch sizes.

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Our single emulsion synthesis services provide the precision, expertise, and support to elevate your project.

Ready to Get a Microfluidic Solutions Quote? Get a Quote Now

Contact us today for a free consultation, and let's collaborate to create emulsions that redefine performance in your industry. Your innovation deserves nothing less than the best. Partner with us to make it a reality.