Microfluidics system can process small quantities of fluids by using tiny channels with dimensions at the microscale - usually tens to hundreds of micrometers. In the past decade, a number of novel techniques and materials have been applied to microfluidic systems. Meanwhile, integrated microfluidic chips have become powerful platforms for high sensitive, high throughput, and low-cost analysis. With years of experience and advanced microfluidic platforms, Creative Biolabs offers one-stop microfluidic solutions to meet the unique needs of our clients on microfluidic integrated devices.
Bioanalysis is a crucial part of biomedical analysis, which mainly includes two parts, biological system analysis and biomolecular detection. In the recent years, scientists focus on three areas: 1) integration and miniaturization of analytical devices for point-of-care (POC) testing, 2) analyzing at single-cell or single-molecule level to obtain critical information about the heterogeneity of certain population, as well as 3) high-throughput screening for large-scale analysis. In order to solve these problems, microfluidic techniques are under rapid development, which revolutionize the way for sampling, sample separation, mixing, chemical reaction, and detection.
Microfluidic is also called laboratory on a chip (LOC). Since development, microfluidic technologies have revolutionized the way for experimental biology and biomedical research, along with significant improvements in fields of chemical synthesis, biofabrication, drug screening, and organ/tissue modeling. Importantly, microfluidics can integrate with POC testing to achieve high sensitivity, portability, and specificity. Recently, the application of microfluidic devices in the bioanalytical field has grown rapidly, such as achieving the “sample-in/result-out” analysis mode, precisely tuning the size and pattern of nanoparticles for drug delivery, as well as discovering and screening new chemical entities.
Usually, a microfluidic chip is composed of distinct compartments of inlet, channel mixer, and signal detector. Nowadays, the development of micro-/nanofabrication techniques eases the manufacturing of individual microfluidic component, which will then be assembled to make a functional chip. To date, several materials can be used in microfluidic chips, including organic materials (e.g., polydimethylsiloxane, or PDMS, polystyrene, or PS, polymethyl methacrylate, or PMMA, and paper), inorganic materials (e.g., silica and glass), and composite materials.
Fig.2 Improving microfluidics-based immunoassay by employing advanced materials and techniques. (Yang, 2019)
After years of exploration, we have built some advanced platforms, such as MDR Detection Systems, CTC Detection Systems, Single-cell Sequencing, Single-cell Molecular Cloning and Screening … With experienced scientists, we offer one-stop microfluidic solutions to help our clients remove the obstacles of your projects and make breakthroughs.
With Ph.D. level scientists and over a decade of experience in microfluidic systems, Creative Biolabs is dedicated to serving the unique needs of our clients by providing services that are tailored to meet your R&D timeline and budget. Please contact us for more information and a detailed quote.
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