Traditional bubble-making methods like stirring or ultrasound produce uneven bubbles, limiting reliability. Our microfluidic approach fixes this by using precision-engineered chips to create bubbles with consistent size, stability, and properties.
Creative Biolabs specializes in custom gas bubble synthesis chip development, offering end-to-end support from conceptual design to functional validation. Our microfluidic platforms enable precise manipulation of gas and liquid phases, ensuring reproducible bubble formation across varying flow rates and operational conditions.
We start with a free consultation. Tell us your bubble specs (size, material, quantity), timeline, and budget. We’ll share initial ideas and let you know if we can meet your needs—no hard sell, just honest feedback.
Our engineers design your custom solution (or adapt a standard one) and share a model for your approval. Once you sign off, we build the chip or system using precision machining for fast, accurate results.
We test your system to confirm bubble quality and performance. For lab-scale orders, we ship the bubbles ready to use. For systems, we include setup guides and a training session—so you’re up and running fast.
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Client Testimonials
"We collaborated with them for our cell culture and microbubble needs, and their team was responsive to our specific requirements. The product performed as expected, and their post-delivery technical guidance helped streamline our experiments smoothly."
— Dr. Clara Bennett, Senior Research Scientist
"Working with Creative Biolabs on custom microbubble synthesis was straightforward. They communicated project progress clearly and delivered a consistent, reliable product that integrated well with our existing research workflows."
— Mark Henderson, R&D Manager
"We relied on Creative Biolabs for scalable microbubble production, and they delivered on time without compromising quality. Their support team addressed our questions promptly, making the entire collaboration hassle-free."
— Sarah Collins, Process Engineer
"The custom microfluidic system has improved the reproducibility of our experiments. Their team provided clear setup instructions, and any follow-up issues were resolved efficiently—great partner for research-focused projects."
— Dr. Michael Torres, Lab Director
Published Data
Protein crystallisation with gas microbubbles as soft template in a microfluidic device
Lysozyme crystallisation was first-time performed in a microfluidic device in the presence of different gases: helium, nitrogen, oxygen, and carbon dioxide microbubbles. The microfluidic system has been designed to generate the gas bubbles and to observe the crystallisation process with gas bubbles, which can be used in screening and optimisation of the crystallisation conditions for biomaterials. There are advantages to use microfluidic for optimisation the crystallisation process with limited expensive biomaterials, and it is also able to observe the crystal growth process under optical microscope, the restriction of the microfluidic is the scalability, as the conditions explored in the microfluidic system need to be transferred to larger-scale crystallization processes.
Fig.1 Schematic set-up for protein crystallisation and microscopic image of bubble formation inside the microfluidic chip.1,2
References
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Tian, Wenqing, et al. "Protein crystallisation with gas microbubbles as soft template in a microfluidic device." Molecular Systems Design & Engineering 8.10 (2023): 1275-1285. https://doi.org/10.1039/D3ME00058C
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Distributed under Open Access license CC BY 3.0, without modification.
Created December 2025
