Microfluidic Chip Development for Protein Solution

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Currently, microfluidic chip development has aroused great attention in many clinical settings. To meet the challenging requirements, Creative Biolabs has built a team of experienced scientists with facilities and processes designed specifically to provide the best strategy and protocols customized to microfluidic chips studies. We have accomplished many projects and have delivered numerous microfluidic chips in a range of therapeutic areas.

Introduction of Microfluidic Chips

Microfluidic chip has proven its important role in many areas of practical applications, such as clinical diagnosis, drug development, and cell biology. Microfluidic chips consist of a series of linking microchannels through which different types of fluids are injected and controlled, allowing the regulation of many parameters at a single-cell level. Nowadays, microfluidic chips can be made of several raw materials, including silicon, glass, and polymers. Many studies demonstrated that microfluidic chips are also essential to several protein-related studies, like protein interaction analysis, protein expression profiling, protein quantitation detection, as well as protein modification studies.

The data indicated that microfluidic chips are rapid, high efficiency, throughput, and specificity methods for proteins and proteome measurements ranging from protein crystallization to differential expression profiling of protein samples. For example, microfluidic chips are broadly used for a wide spectrum of protein-protein interaction analysis, especially for antigen-antibody interactions. The protein receptors or specific antibodies will be injected into microfluidic chips to further bind to target proteins by using multiplex microchannels. The binding specificity can be determined by detecting the flow rate on the channels.

Microfluidic platforms for intact cell analysis. Fig.1 Microfluidic platforms for intact cell analysis. (Liu, 2013)

Our Microfluidic Chips platform for Protein Solutions

Microfluidic chip became a powerful strategy and has been utilized in many protein and proteomics researches. They offer a one-stop platform for tiny volume sample preparation, extraction, and detection, with the benefit of reduced analysis time, improved detection limits, and high throughput.

Creative Biolabs offers a comprehensive and well-mature platform for designing and developing your own microfluidic chips. By focusing on quality and scientific expertise, our scientists are dedicated to producing various kinds of microfluidic chips with the highest standards for protein studies applications. Whether you need support with the chip design or for the whole chip development process, we are always your good partner. In the past few decade, we have accomplished a battery of microfluidic chips for our valued clients and they have been widely used for many protein-associated applications, such as protein structure characterization and protein sample quantitation.

In recent studies, a novel microfluidic chip was generated by our labs for measuring allergic pathways at a single-cell scale. This chip is the integration of materials, fluidics handling, and hardware that enables analyze cell lysate with high sensitivity and affinity. Currently, our services are mainly focused on developing different microfluidic chips for protein-based analysis, including but not limited to:

Creative Biolabs has developed a novel protein-related microfluidic chips design and development platform to remove the obstacles of your projects and bring breakthroughs. Our scientists specialized in this area will work with you to develop the most appropriate strategy that will offer the most meaningful data for your research. If you are interested in our services, please feel free to contact us or send us an inquiry.

Reference

  1. Liu, Y.; et al. Microfluidic platforms for single-cell protein analysis. Journal of laboratory automation. 2013, 18(6): 446-454.

For Research Use Only. Not For Clinical Use.

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