Electrode Microfluidic Chip Products

Introduction Application Published Data

Creative Biolabs offers advanced electrode chip processing technology designed to support realizing your innovative ideas. Our technology enables efficient development and implementation, helping transform concepts into tangible solutions.

Why Integrate Electrodes into a Microfluidic Chip?

Metal electrode microfluidic chip is a chip that combines microfluidic technology and metal electrode design. Microfluidics chip itself is a technical platform for operating and controlling fluids at the micrometer scale. It realizes the precise manipulation, mixing, reaction, separation and detection of fluids through a microchannel network. The addition of metal electrodes enables this chip to use electric field effects to perform more complex operations, such as electroosmosis, electroporation, electrophoresis separation, etc.

Fig. 1 Microfluidic chip with electrode. (Creative Biolabs Original)Fig. 1 Microfluidic chip with electrode fabricated by Creative Biolabs.

Metal electrodes are usually used to generate electric fields in microfluidic chips. These electric fields can interact with the fluid in the chip to change the behavior of the fluid or trigger specific chemical reactions. For example, in electrophoresis separation, the electric field generated by the metal electrode can separate charged particles in the fluid according to charge and size; in electroporation research, the electric field can be used to form small holes in the cell membrane, so that the substances in the cell can be exchanged with the outside world.

Fig. 2 The dielectrophoresis-based micro-separator.Fig. 2 Schematic of the dielectrophoresis-based micro-separator.1,3

Applications of Electrode Integrated Microfluidic Chip

Using metal electrodes on the chip to generate an electric field, combined with capillary electrophoresis technology, to achieve rapid separation and high-throughput sequencing of DNA.

Using electric fields to precisely manipulate cells to achieve cell capture, separation and purification.

By integrating metal electrodes and other components on the chip, the microenvironment of the organism is simulated to culture and study cells, tissues and organs.

Using metal electrodes in microfluidic chips to perform electrochemical reactions, compounds with specific structures and functions are synthesized.

Detecting electron transfer in chemical reactions through metal electrodes enables sensitive detection of trace chemicals.

Published Data

The following are results highlighted in articles related to the electrode-integrated microfluidic device:

Fig. 3 The schematic of the dielectrophoretic microfluidic device.Fig. 3 The design of the dielectrophoretic microfluidic device.2,3

A PDMS microfluidic chip containing channels and electrodes was made that was able to effectively separate polystyrene particles of different sizes. The device was fabricated in PDMS (polydimethylsiloxane) using a 3D printed mold containing the channel and electrode patterns. The comb-shaped electrodes on the chip are made by filling the electrode stamp with silver conductive paint.

Fig. 4 The separation result of the microfluidic chip.Fig. 4 The separation result of the chip.2,3

When operating the device at ±12 V, the particles can be separated. The blue color in the figure is the trajectory of particles with a size of 10 μm, and the green color is the trajectory of particles with a size of 3 μm.

Creative Biolabs provides more detailed information about electrode-integrated chips. You can directly contact our experts to discuss your needs. We will evaluate your ideas comprehensively and provide feasible, cost-effective solutions. You can directly contact our experts to discuss your needs. We will evaluate your ideas comprehensively and provide feasible, cost-effective solutions. For further details, please feel free to contact us.

References

  1. Dalili, Arash, et al. "Parametric study on the geometrical parameters of a lab-on-a-chip platform with tilted planar electrodes for continuous dielectrophoretic manipulation of microparticles." Scientific reports 10.1 (2020): 11718.
  2. Valijam, Shayan, et al. "Fabricating a dielectrophoretic microfluidic device using 3D-printed moulds and silver conductive paint." Scientific Reports 13.1 (2023): 9560.
  3. Distributed under Open Access license CC BY 4.0, without modification.

For Research Use Only. Not For Clinical Use.



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