Microfluidic Technology Platforms

Inquiry

Currently, advances in microfabrication and microfluidics offer new approaches for drug analysis, such as active testing, drug screening, and the study of metabolism. To date, several microfluidic chip technologies are developing rapidly, including three-dimensional (3D) cell culture, lab-on-a-chip technology, droplet techniques, organs-on-chip…… As a CRO service provider in the microfluidic field, Creative Biolabs has developed a range of advanced technology platforms. We are confident in providing the best products and services to meet our customers’ special requirements.

MDR Detection Systems

Fig. 1 Microfluidic Technology Platform. (Creative Biolabs authorized)

Creative Biolabs provides the design, development and customization services of multidrug resistance (MDR) rapid detection system based on microfluidic technology. In AST, the application of the microfluidic system makes it possible to carry out antibiotic susceptibility test on a single cell level, which provides a broad prospect for rapid and accurate determination of antimicrobial susceptibility spectrum to guide antibiotic treatment decisions.

CTC Detection Systems

Fig. 2 Comparison of circulating tumor cells and cell-free DNA as blood-based biomarkers in oncology. (Lowes, et al., 2016)

CTC is described as the cells released into the vascular system by the primary tumor and it is very important to detect CTC in blood for evaluating metastasis process and guiding treatment. Creative Biolabs provides design and customization services for CTC testing devices based on microfluidic technology, such as the HTMSUs microfluidic device that detects the unique electrical characteristics of CTC through the integrated platinum conductivity sensor……

Single-cell Sequencing

Fig. 3 Microfluidic Technology Platform. (Creative Biolabs authorized)

Microfluidic technologies are valuable and attractive for single-cell manipulation owing to strict handling and low risk of contamination. At Creative Biolabs, we offer several types of sequencing methods, including microfluidic droplet-based single-cell sequencing (Drop-seq), Microfluidic diffusion-based single-cell RNA sequencing (scRNA-seq), Microfluidic single-cell whole-transcriptome sequencing……

Single-cell Molecular Cloning and Screening

Fig. 4 Microfluidic Technology Platform. (Creative Biolabs authorized)

Tackling heterogeneous cells at single-cell resolution is increasingly significant in different branches of biological and biomedical subjects. At Creative Biolabs, our microfluidic equipment is used upstream of cell trapping, isolation, manipulation, and genetic analysis methods, these techniques permit high purity retrieval of viable cells with the specific marker. We provide microfluidic integrated solutions for simple, fast, and robust single-cell molecular cloning and screening for worldwide customers.

Microfluidics-Based Nanomedicine Development

Fig. 5 Microfluidic Technology Platform. (Creative Biolabs authorized)

The microfluidic method is a versatile technology in the generation of nano- or micro-sized drug delivery systems, analysis of compounds, and assessment of the produced nanoparticles. As an experienced specialist in the microfluidic technology, Creative Biolabs has a strong capacity to design efficient microfluidic chips to prepare nanoparticles, including drug nanosuspensions, polymer nanoparticles, theragnostic nanoparticles, structured nanoparticles……

Point of Care Technology (POCT)

Fig. 6 Microfluidic Technology Platform. (Creative Biolabs authorized)

Point-of-care technology (POCT) diagnostic systems are tools that can rapidly lead to in vitro diagnostic (IVD) results by non-trained personnel at a patient site in a variety of locations such as the field, the home, the ambulance, or the hospital. Quick analysis time and high sensitivity are the most important characteristic of current POCT diagnostic systems. Creative Biolabs provides one-stop microfluidic integrated solutions for POCT to help customers accomplish multiple point-of-care experiments.

If you are interested in our Microfluidic Technology Platform, please feel free to contact us for more details.

Reference

  1. Lowes, L.E., et al. Circulating tumor cells (CTC) and cell-free DNA (cfDNA) workshop 2016: scientific opportunities and logistics for cancer clinical trial incorporation. International Journal of Molecular Sciences, 2016, 17(9): 1505.

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