Biosensor Development Services
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Combining cutting-edge engineering knowledge and biotechnology, Creative Biolabs is confident to assist our clients around the world to design, develop and fabricate high-quality, high-safety and high-flexibility biosensors.
Microfluidic Biosensors
Sensitive detection of biological and chemical species is crucial to many frontier disciplines, including bioanalysis, disease diagnosis, drug development, chemical analysis and agricultural development. Integrating various functional units and structural modules allow biosensors to be used in many immediate applications, such as healthcare, sports monitoring, pollution analysis, environmental monitoring, forensics, chemical synthesis or biological detection. The integration of microfluidic channel systems and biosensors provides an inexpensive, simple and flexible multiplex detection theory for biochemical analysis. Microfluidic solution delivery systems directly guide sample flow, control reaction time and reaction progress. Closed equipment further reduces sample requirements and eliminates the loss of limited samples. The submillimeter-scale laminar flow properties allow users to accurately predict liquid flow, flexibly control and perform a series of beneficial operations, and even manipulate local molecular concentrations through diffusion mixing. In addition, the reaction in the microchannel has a larger surface area, so that basic motions such as heat exchange can be performed more efficiently.
Fig 1. Classification of biosensors. (Creative Biolabs)
Services at Creative Biolabs
Reliable and accurate microfabrication equipment and cutting-edge biological knowledge allow us to assist our clients to integrate diversified analysis and diagnostic methods into the sub-millimeter scale at an excellent cost. Our services will include but not be limited to:
Electrode miniaturization has reshaped the field of electrochemical sensing. The integrated design of electrochemical systems with microfluidics and multiple sensing arrays provides unprecedented opportunities for the detection of biological events with high spatial and temporal resolution. Integrated and reliable microfluidic electrochemical sensors transfer traditional immunological experiments to the micron scale, and quantitatively convert biological signals into electrical signals that can be exported. With our help, you will have the opportunity to refine current strategies and apply them to demanding sensing domains, reconfiguring your electrochemical sensing configurations in a precise and controllable manner.
Fig 2. Miniaturized electrochemical microfluidic sensor. (Salim, et al., 2018)
Microfluidic technology has greatly promoted the development of point-of-care (PoC) devices. Compact and low-cost microfluidic systems provide ideal and diverse functions for PoC devices, and diversified biomarker analysis technologies provide real-time medical diagnosis for patients in resource-limited settings. We will help our clients complete the expansion and simplification of laboratory research in the clinical field, and provide portable and low-cost solutions for complex and expensive analysis procedures in the laboratory.
Recent advances in lab-on-a-chip research have established a solid foundation for wearable biosensors. As a miniature alternative to macroscopic analysis and reagent pretreatment, microfluidic systems bring endless possibilities to traditional wearable sensors. We provide our clients with flexible and rapid prototyping to help them explore and develop more possibilities for in-situ biofluid detection.
Microfluidic impedance biosensors concentrate the enrichment, capture, detection, and analysis of samples into submicron channels, and convert the concentration of detection molecules into electrochemical impedance signals accurately and quantitatively. Cutting-edge fluid flow engineering and microfabrication technology allow us to maximize the efficiency of impedance biosensors, use fluid mechanics to manipulate tiny biosensors and broadly explore the infinite possibilities of this interdisciplinary area.
Don't hesitate to contact us to discuss your need and for more information.
Reference
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Salim, A.; et al. Review of recent metamaterial microfluidic sensors. Sensors. 2018, 18: 232.
For Research Use Only. Not For Clinical Use.
