Creative Biolabs provides a full range of state-of-the-art organ-on-chip services, crafted to help you launch and advance your research projects smoothly. We've focused exclusively on organ-on-chip research, development, and applications. Our diverse products are now used by pharmaceutical companies worldwide.
Custom microfluidic fabrication services refer to professional solutions for designing and manufacturing tailored microfluidic devices—such as chips with precise microchannels—using materials like PDMS, glass, or polymers, to meet specific fluid-handling needs in fields like biomedicine and chemical analysis. Beyond delivering custom designs that meet precise fluid dynamics criteria, our solutions ensure material compatibility with biological/chemical environments while balancing precision and cost efficiency throughout the process from prototyping to mass production.
Fig. 1 A three-layer structure comprising a fluidic, flexible PDMS membrane and control layers.1,3
Our design process begins with taking your specific needs and turning them into working microfluidic designs. We tailor solutions to your specific needs, whether you require cell sorting chips with precise laminar flow control or diagnostic devices with integrated fluid delivery systems.
Material Science Expertise
Selecting the right material is critical to performance. Our portfolio includes:
Material | Applicable Occasion |
PDMS | For biological applications requiring flexibility and gas permeability |
Glass | When optical transparency and chemical resistance are paramount |
PMMA | Cost-effective solutions with excellent mechanical properties |
Specialty polymers | For high-temperature or corrosive environments |
Our processing capabilities, ranging from injection molding to anodic bonding, ensure that your material selection translates into reliable, production-ready components.
Scalable Production
Make the seamless move from prototype to volume production with our scalable manufacturing solutions. We also provide specialized quality control protocols, which we strictly adhere to during production. This ensures every unit meets final standards for both dimensions and functionality, so you won't have to worry about variations between production batches.
We begin by getting a clear understanding of your application goals, performance requirements and constraints. Our technical specialists work with your team to define success criteria, from fluid volume parameters to regulatory compliance needs.
Engineering & Simulation | Before physical manufacturing begins, our designers will create a 3D model for your custom solution. By running simulations on the model, we identify potential issues, resolve them, and optimize design performance, thus eliminating unnecessary waste. |
Prototype Development | We ensure functional prototypes are built using materials and processes consistent with their final application, and subject them to rigorous testing to guarantee error-free production of the final product. |
Iterative Refinement | We refine designs to boost performance based on test results. This collaborative process keeps going until your prototype meets all specifications. |
Prototype Development | For volume orders, we scale production while maintaining strict quality control. Every batch includes validation testing to ensure consistency with your approved prototype. |
"Their custom microfluidic fabrication service met our lab's requirements well. The team clarified technical details upfront, used the biocompatible material we specified, and the final devices had no issues."
— Sarah L., Research Director
"We worked with them for custom microfluidic chips, and the process was straightforward. They adjusted the channel design to fit our sample volume needs, delivered on time, and the chips performed reliably in our initial flow tests."
— Michael T., Process Engineer, Pharmaceutical Manufacturer
"We needed a tailored microfluidic system for cell sorting, and they delivered. The fabrication quality was consistent, they addressed a minor design tweak quickly, and the device integrated smoothly with our existing equipment."
— Dr. Elena M., Biomedical Researcher
"We provided our microfluidic specs, they double-checked key dimensions, and the finished chips matched our requirements. Post-delivery support was also responsive."
— James K., MedTech Entrepreneur
"For our diagnostic tool project, their custom microfluidic fabrication worked well. They balanced precision with turnaround time, the flow control in the devices was accurate, and they kept us updated throughout the process."
— Dr. Rajiv P., Chemical Engineer
Lung adenocarcinoma cells selection by cavity-added serpentine microchannels
A novel microfluidic device specifically designed for isolating human lung cancer cells in microchannels utilizes magnetic nanoparticles to enable target A549 cells immobilized on magnetic beads to be manipulated and captured in cavities by an external magnetic field, exhibiting excellent cell separation performance. This system combines magnetic beads with target cells through selective binding via aptamers.
Fig. 2 Schematic of the proposed SMAC microfluidic device, including a glass substrate, a polydimethylsiloxane (PDMS) channel and an external magnet for capturing A549 cells.2,3
Red blood cell deformability assessment in continuous flow with microfluidic devices
A study presented a novel integrative microfluidic device able to perform continuous separation of a desired amount of blood cells, without clogging or jamming, and at the same time, capable to assess the deformation index (DI) of both WBCs and RBCs. The microfluidic device used in a study was designed to include a cross-flow filtration barrier and several sequences of hyperbolic channels in the outlet of the sub-channels.
Fig. 3 Blood cells flowing through cross-flow filtration barrier to the direction of the outlets and hyperbolic chamber.2,3
References
Created August 2025
We deliver precise, reliable custom fabrication services to support your work—whether you're developing breakthrough diagnostic tools, optimizing industrial processes, or advancing scientific research.
Contact us for a quick consultation to discover how we can speed up your journey from concept to commercialization.