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Creative Biolabs provides our clients with customization, design and fabrication services for microfluidic systems. Our stable, cutting-edge, high-precision microfluidic fabrication services will help you customize functional chips to fulfill functional expectations and experimental needs.
Due to unique technical advantages such as miniaturization, integration, and multi-function, microfluidic chips have been widely used in the fields of analysis, detection, and biological research. As an emerging technology in the field of biological experiments and chemical synthesis, our stable and high-precision processing technology ensures the operability and function of the chip in practical applications. Our service will include a complete workflow from upstream material selection and structural design to downstream detection experiments that you may freely choose the entering and exiting point.
Fig 1. Workflow of microfluidic fabrication. (Creative Biolabs)
Processing experience and cutting-edge microfabrication concepts allow us to provide fabrication techniques.
Traditional fabrication techniques of microfluidic manufacturing are mostly inherited from the metal and semiconductor machining industries. These engineering techniques developed in depth over the years have been well-defined and perfectly characterized.
Photolithography is the most commonly used stable fabricate technology with the highest resolution for microfluidic manufacturing. It is used to produce silicon or glass channels with micron-level resolution. Photolithography also processes patterned molds to reprint high-precision silicon elastomer chips with well-defined structures. In addition, laser engraving, precision casting and microinjection have also been used in the manufacture of various polymer chips. Creative Biolabs evaluates various micro-manufacturing approaches comprehensively based on material, structure and expected precision, providing our clients with the most cost-effective and applicable micro-fluidic chip manufacturing process.
The versatility and simplicity of 3D printing have rapidly made it an important method for the production of polymeric microfluidic devices. 3D printing directly embeds channels with different precision, height and shape in the polymer block and avoids the bonding, packaging or drilling processes in conventional production. 3D printing has flexibility unmatched by conventional manufacturing methods. After importing the design drawings, the chip can be directly constructed. Creative Biolabs provides a variety of 3D printing processes including SLA, FDM, and thermoplastic extrusion for our clients and provides them with fast and repeatable prototype construction and small-scale chip manufacture. However, it should be noted that the 3D printing process greatly limits the optional range of selectable materials.
Silicon is the earliest material used to manufacture microfluidic chips. It has the advantages of resistance to organic solvents, excellent mechanical properties, good thermal conductivity, good electrical conductivity, and easy metal deposition. Silicon chips are often used in the biological field, especially in cell research like cell trap, because they can process precise structures. Although silicon is gradually being replaced by polymers or glass, silicon processing is still very important for microfluidic chip manufacturing, such as making molds for PDMS chips. At the same time, Creative Biolabs provides customers with a variety of high-precision silicon chip processing processes, including photolithography, wet etching, and dry etching.
Microneedles refer to arrays of microneedles ranging in size from 25 microns to 2000 microns, which can be used for drug delivery, interstitial fluid sampling and disease diagnosis. The materials used to make microneedles include silicon, metals and polymers, among which PDMS is often used as a mold for making soluble microneedles. Microneedles have different shapes for different functions, including solid, hollow and coated microneedles. The advantages of microneedles are minimally invasive, simple operation, safer and low risk of infection. At the same time, microneedles are often in the form of patches or directly connected to applicators, which do not require much training. Creative Biolabs provides customers with comprehensive costume microneedle fabrication service, silicon microneedles, PDMS microneedle mold and 3D printed microneedles.
Creative Biolabs possesses abundant experience in microfluidic chip design and fabrication, complete microfluidic background research, well-trained staff member, leading microfluidic processing equipment and mature technology. We provide microfluidic chip development services for our clients all over the world to help you maximize the advantages of microfluidic components, bring your design ideas into reality, and explore new possibilities in biology and chemistry. Please don't hesitate to contact us for any needs.
For Research Use Only. Not For Clinical Use.