Microfluidics-Based Analysis in Veterinary Diagnostics

Inquiry

The powerful microfluidic technology platform enables Creative Biolabs to provide our clients with stable and reliable one-stop solution services for microfluidic veterinary diagnostic analysis systems, providing a new tool for reforming agriculture and animal husbandry.

Microfluidic System for Veterinary Application

The globalization of animal husbandry and trade in animal products has greatly increased the risk of the rapid spread of disease or disease-causing pathogens, leading to more urgent problems in animal health, disease surveillance, and microbial management in agriculture and livestock. Microfluidics can combine bioanalytical techniques, animal genetics, cell biology, veterinary science and many other scientific disciplines, allowing users to flexibly access minute quantities of biological materials. Although still in the early stages of development, microfluidic systems show irreplaceable application potential in livestock feeding and product processing. The application of microfluidic technology in veterinary medicine mainly covers the synthesis of drug delivery systems, disease detection and pathogen control.

Drug Delivery

Miniaturized microfluidic systems allow manipulation of microliter or even nanoliter liquids, and drug-encapsulated gel microspheres with good surface properties can be easily produced using droplet generation technology. Compared with other methods, these smart small drug delivery systems deliver the package to the right place more efficiently and achieve the preset effect with a smaller dose, which means less antibiotic/chemical use and healthier animal products.

Disease Detection

Various biochips and sensors have been widely used for early disease monitoring in animals. Test paper and flow sensors produced by the paper-based microfluidic principle provide a low-cost, rapid and reliable diagnosis for companion animals and livestock infectious diseases. These decentralized diagnostics do not require professional training or instrument support, only need simple operation steps from sample collection to result in output, which minimizes the possible risk of animal stress when collecting samples. When more accurate detection results are required, the miniaturized and integrated microfluidic nucleic acid detection chip can complete sample processing, nucleic acid amplification and result output with only a small amount of equipment support, providing a field-deployable solution for traditional veterinary diagnosis.

Fig 1. Paper microfluidic chips for veterinary testing. (Tholoth, et al., 2021)

Pathogen Control

Microfluidic devices integrating sensing, detection, and control systems can significantly guard the safety and quality of agricultural and animal products. Functionalized wearable devices have the ability to track all stages of the life cycle of animal products from birth to sale, enabling real-time monitoring and rapid response to pathogens. Simple detection devices are used to detect antibiotics, additives or unauthorized antimicrobial/fraudulent substances in serum, meat or animal products.

Creative Biolabs is confident to help our clients use microfluidic technology in veterinary diagnosis and animal husbandry more widely and valuable. We fully consider the specific needs of animal health and the integration conditions of microfluidic systems, develop and construct suitable microanalysis systems or paper-based analyzers for our customers. With our help, you can maximize the unlimited potential of microfluidic technology. Our close cooperation will help you develop new technologies, improve existing technologies, and greatly advance microfluidic chips application in veterinary diagnosis, so don't hesitate to contact us for more information.

Reference

Tholoth, M.; et al. Molecular detection of infectious laryngotracheitis virus in chickens with a microfluidic chip. Animals. 2021, 11, 3203.

For Research Use Only. Not For Clinical Use.