• Home
• SERVICES
• One-Stop Microfluidic Solutions
• Droplet Generator and Flow Chemistry
• Particle Synthesis
• Polymer Nanoparticle Synthesis

By focusing on quality, scientific expertise, flexibility, and responsiveness, scientists and staff at Creative Biolabs are dedicated to providing a flexible and expedient microfluidic solution to meet global regulatory standards. Experienced teams of researchers and technicians have enabled our company to create an environment to undertake any research to the highest of standards with a knowledge that spans a full range of particle synthesis and therapeutic areas.

Introduction to Polymer Nanoparticle

Polymer nanoparticles have attracted much attention due to their significant applications in different areas of disease treatment. In general, Polymer nanoparticles are composed of nanocapsules and nanospheres. Nanocapsules are designed by using an oily core for dissolving chemicals and a polymer shell for regulating drug release. Nanospheres are a series of polymer networks that are generated for the adsorption and retention of drugs. In the past few years of studies, polymer nanoparticles have shown promising results in the field of smart drug delivery. Polymer nanoparticles can deliver compounds to the target site of action, with high accuracy and high efficacy. Moreover, a large number of techniques, including emulsion, solvent evaporation, and supercritical fluid technology, have been developed for producing polymer nanoparticles.

Fig.1 Schematic representation of the structure of nanocapsules and nanospheres. (Zielińska, 2020)

Microfluidic Solutions for Polymer Nanoparticle

Currently, polymer nanoparticles have been considered effective drug delivery systems and hold great potential for the treatment of various human diseases. However, lack of suitable technologies for rapid screening and evaluating polymer nanoparticle-based delivery systems related to in vivo studies. As a result, microfluidic technologies have become novel methods for polymer nanoparticle preparation, synthesis, as well as toxicity assessment. Pilot studies have indicated that microfluidics can not only produce nanoparticles in a fast, repeatable, and high-throughput manner but also create a three-dimensional flow environment to simulate physiological and pathological processes.

As a well-established company in the bio-industry, Creative Biolabs has established the utmost efficient integrated microfluidic solutions to innovate and accelerate your polymer nanoparticle project process. Equipped with a team of professional scientists, we have established a panel of microfluidic technologies for our clients to study the properties of polymer nanoparticles, to design a new class of microfluidic-based polymer nanoparticles, evaluate the safety of your polymer nanoparticle delivery systems, and produce novel polymer nanoparticles. Particularly, all the nano-particulate systems are designed to be formulated without damaging the active ingredients of the drug.

Advantages of Microfluidic for Polymer Nanoparticle

Nowadays, polymer nanoparticles have proven their effectiveness in preventing and protecting candidate drugs, like antibodies, proteins, or peptides, from many kinds of environmental hazards. Furthermore, polymer nanoparticles also play an important role in gene delivery. In our labs, a battery of assays for fabricating polymer nanoparticles has been generated. Therefore, we provide global solutions for polymer nanoparticle development, a seamless, high-quality, single-source value chain from discovery to commercialization.

• In vivo rapid screening of nanoparticles
• Good biocompatibility
• Easy design and preparation
• Nano-scale to micro-scale sized particles
• Easy for storage and easy to transport
• High batch-to-batch consistency

With years of operational experience, Creative Biolabs can provide advanced microfluidic services for polymer nanoparticle synthesis projects. Our scientists specialized in microfluidic technology studies will work with you to establish the most appropriate strategy. Now, we have developed efficient methods to anticipate challenges, overcome difficulties and convert various potential polymer nanoparticles into commercial products. If you have any special needs in our services or be interested in learning more about our company, please feel free to contact us for more details.

Reference

1. Zielińska, A., et al. Polymeric nanoparticles: production, characterization, toxicology, and ecotoxicology. Molecules. 2020, 25(16): 3731.

For Research Use Only. Not For Clinical Use.