Polyacrylamide Particle Synthesis Service

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Creative Biolabs is one of the well-recognized experts who are professional in applying advanced microfluidic technologies for a broad range of project objectives. To fill the gaps in this field of polyacrylamide particles, we will try our best to provide a customized proposal to meet your project requirements in the quality, timeline, and budget.

Introduction of Polyacrylamide Particles

Polyacrylamide (PAM) is a type of hydrogel, which is composed of a loosely cross-linked acrylamide structure. Due to the ability to hold a large amount of water, the PAM has been widely used as a biomaterial for various applications, such as soft contact lenses, implants, and drug delivery particle systems. In addition, because of its easy surface functionalization, it has recently been used in various microencapsulation applications, including enzyme immobilization, controlled release, RNA capture, and drug encapsulation.

Microfluidic-based Polyacrylamide Particles

Nowadays, the growing need for specific polyacrylamide particles becomes more dominant. As a novel technology, the microfluidic provides a method for the production of polyacrylamide particles in sizes ranging from 20 to 220 µm. Using microfluidic devices, discrete objects, such as particles and cells, can be loaded to polyacrylamide soft deformable beads, which is necessary for chemical and biological assays.

Fig.1 Morphology of PAM gel particles. (Demaree, 2018)

Some studies showed that the polyacrylamide particle structure allows the transfer and exchange of growth materials via the nanopores. The beads’ size can largely impact the cell growth speed and drug/agrochemicals degradation speed. Recently, the polyacrylamide-based hydrogel particles (PHPs) have been used in oil recovery applications due to their special swelling and dissolving properties. In addition, the PAM gel particle temporary plugging agent has a certain salt tolerance.

Fig.2 Scanning electron microscope images of the cross-section of PAM gel particles. (Demaree, 2018)

Advantages of Microfluidic-based Polyacrylamide Particles

High reproducibility
Real-time control
Reduction of waste
Improved efficiency of loading techniques and encapsulation yields
Fully customizable experimental design to expand beyond standard procedure
Competitive price with the best quality
Extensive experience and advanced biotechnologies

Based on our advanced platforms, we can provide novel polyacrylamide particle production services for our clients all over the world. According to precisely controlling the formation of the bead, we are able to produce polyacrylamide particles with well-defined sizes, shapes, and morphologies. If you are interested in our services, please do not hesitate to contact us for more detailed information.

Reference

Zhang, D.; et al. Facile droplet microfluidics preparation of larger PAM-based particles and investigation of their swelling gelation behavior. e-Polymers. 2019, 19(1): 579-593.

For Research Use Only. Not For Clinical Use.