Microfluidic Development Services for Drug Delivery

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Target drug delivery is a promising strategy for selective and preferential delivery of therapeutic agents to the target site, thus increasing the concentration of the medication in the pathological parts, improving pharmaceutical activity, reducing low side effects. Microfluidic technologies are becoming one of the key technologies in the field of drug delivery, used for fabrication of drug carriers, direct drug delivery systems, high-throughput screening, and formulation and immobilization of drugs. Creative Biolabs has organized a staff of excellent experts who have accumulated rich experience in microfluidic-based drug delivery research. We support a series of top-quality research services of microfluidic-based drug delivery.

Advantages of Microfluidic-based Drug Delivery

Microfluidic technologies have attracted considerable attention in the area of drug delivery science. Compared to conventional delivery methods such as oral, sublingual, rectal, intravenous, subcutaneous, and intramuscular drug deliveries, microfluidic-based drug delivery system offers many advantages such as precise dosage, ideal delivery, target-precise delivery, sustainable and controlled release, multiple dosing, and slight side effects. In addition to these, microfluidics has lower costs for fabrication compared to other traditional fabricated devices and can be fabricated with different miniature devices. Importantly, microfluidic devices allow miniaturized usage of sample and reagent, accurate control of the volume of fluid, and accurate temperature control and rapid temperature exchange. These features enable microfluidic devices to become valuable tools for studying drug delivery systems.

Microfluidic Services for Drug Delivery

Microfluidics in Drug Delivery Research

Microfluidic platforms for generation of self-assembled drug and gene carriers. Fig.1 Microfluidic platforms for generation of self-assembled drug and gene carriers. (Damiati, 2018)

Table.1 Different microfluidics systems and carrier materials used for drug delivery. (Mancera-Andrade, 2018)

Material used Geometry Carrier material Drug Application
Glass Co-flowing Human serum albumin Doxorubicin Hepatic cancer
PEEK and silica tube T junction Poly(methyl acrylate) and poly(acrylamide) Ketoprofen and ranitidine Suppression of gastric irritation effects: bleeding and ulceration
Silicon Flow focusing PLGA Ciclosporin -
PDMS Co-flowing with herringbone shape Liposomes Propofol Anesthetic agent
Quartz Chip Hyaluronic acid and ethylenediamine Dexamethasone Cell differentiation of mesenchymal stem cells
Glass Co-flowing and flow-focusing Polycaprolactone, poly(vinyl alcohol) and poly(ethylene glycol) Bovine serum albumin Protein therapy
PDMS T junction Poly(ethylene glycol) diacrylate 5-fluorouracil Cancer therapy
PMMA V-junction Poly(methylsilsesquioxane) Itraconazole Antifungal drug for infections

Services at Creative Biolabs

Creative Biolabs is a world-leading service provider who is devoted to offering the best microfluidic technology services with high quality and low cost. We are committed to providing end-to-end microfluidic-based drug delivery solutions including program design, implementation, and output. We support not only the custom design and development of a microfluidic-based drug delivery system but microfluidic-based preclinical tests such as dosage development and cytotoxicity studies. If you are interested in our services, please contact us to discuss your project.

References

  1. Damiati, S.; et al. Microfluidic Devices for Drug Delivery Systems and Drug Screening. Genes. 2018, 9(2):103.
  2. Mancera-Andrade, E.I.; et al. Microfluidics technology for drug delivery: A review. Frontiers In Bioscience. 2018.

For Research Use Only. Not For Clinical Use.

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