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Creative Biolabs specializes in the development and application of microfluidic technology. With our powerful precision mold design and fabrication platform, we provide clients all over the world with stable, flexible and cost-effective large-scale rigid polymer hot embossing and micro-injection casting services.

Hot Embossing

The most commonly used material in hot embossing for microfluidic chips production is polymethyl methacrylate (PMMA). Under moderate temperature and high pressure, the material undergoes considerable deformation. Pressing the PMMA sheet onto a pre-processed high-precision silicon or metal template at a controlled temperature can achieve rapid and stable reprinting of the template pattern. This rapid reprinting technique is used for high-precision, high-thickness mass manufacturing or test prototype production of polymers. The materials used in the thermal embossing process are not limited to PMMA, but also include other commonly used plastics in the field of microfluidics, such as PC, PET, PVC, etc.

Fig 1. Hot embossing. (Creative Biolabs)

Micro Injection

Microinjection is a technique inherited directly from the field of plastics processing. The fully molten polymer is injected into the mold cavity using high pressure and vacuum at a temperature above the glass transition temperature. After the system has cooled and de-molded, a solidified structure corresponding to the mold negative can be obtained. Compared with the traditional procedure, micro injection molding is relatively complicated, and mold construction is difficult. But overall, this is the most suitable microfluidic chip processing approach for rapid and ultra-large-scale polymer microfluidic chip production.

Fig 2. Microinjection. (Creative Biolabs)

Related Services

Equipped with complete micromachining equipment, well-trained staff, and well-defined manufacturing technology, Creative Biolabs provides precision machining and mass-production services for all kinds of polymers. Our workflow includes complete upstream and downstream protocols, you may freely choose the entry and exit points that suit your plan.

Our professional technicians will conduct technical evaluations of mold development according to chip designs. We comprehensively analyze important process parameters such as chip appearance, material, thickness, channel size, aspect ratio, precision requirements, tolerances, fabrication scale, etc., to conduct a feasibility assessment for you. Some injection molding critical parameters as follows:

• Chip material: hard polymer (PC, PS, PMMA, PP, COC, COP, etc.)
• Channel size: not less than 100μm
• Aspect ratio: not less than 1:1
• Mold accuracy: no more than ±10%
• Maximum accuracy: about 6μm

With abundant experience in micro-fabrication and knowledge of microfluidics, Creative Biolabs is confident to provide our clients with stable, flexible, high-precision hot embossing or micro injection molding services with high-consistency for rigid plastic microfluidic chips. You may select between hot embossing for prototype testing/rapid production or micro injection molding for mass production. In addition, the complete and cutting-edge microfluidic chip production platform allows us to provide chip surface modification, channel sealing and other back-end processing procedures. Whether for small-scale applications or large-scale production, our one-stop microfluidic chip design and fabrication solutions will be your best choice, so please don't hesitate to contact us for any needs.

For Research Use Only. Not For Clinical Use.