Myocardial infarction (MI) is a life-threatening condition caused by the sudden blockage of coronary arteries, often accompanied by serious consequences such as abnormal electrical signal conduction, ventricular remodeling, and fibrosis. Although traditionalRead More…
Wearable Analyzer Integrating Microneedle and Electrochemical Sensors for In Vivo Monitoring of Glucose and Lactate
Background Continuous monitoring of clinically relevant biomarkers in interstitial fluid (ISF) using microneedle (MN)-based assays has the potential to transform healthcare. Researchers from McMaster University have proposed an integrated system, called theRead More…
Detection of H₂S and H₂O₂ in Cancer Tissues Based on Microfluidics
Reactive sulfur species (RSS) and reactive oxygen species (ROS) are closely related to the physiological and pathological processes of redox reactions and oxidative stress. Hydrogen sulfide (H₂S), a reactive sulfur species, hasRead More…
Morphologically Reconfigurable Magnetic Micropillar Array for Particle Capture and Droplet Manipulation Using Acoustic Streaming Effect
Accurate and efficient particle and droplet manipulation is crucial for disease diagnosis, targeted drug delivery, and sample purification. Particle and droplet manipulation based on specific microstructures has been widely used in biologicalRead More…
Application of Droplet Microfluidics in Cancer Research: From Single Cell Analysis to 3D Cell Culture
Cancer remains a formidable challenge due to its difficulty in detection. It has become the second leading cause of death worldwide. The main reasons for the poor efficacy of cancer treatment includeRead More…
Flexible Hemline-Shaped Microfibers for Liquid Transport
Recently, an article titled “Flexible hemline-shaped microfibers for liquid transport” was published in Nature Chemical Engineering. The authors of this paper studied a flexible half-shaped microfiber prepared using microfluidics for directional liquidRead More…
Quantitative Analysis Method of Enzyme Activity at Single Molecule Level Based on Molecular Programming and Droplet Microfluidics
Protein analysis at the single-molecule level reveals heterogeneous behaviors that are often obscured by ensemble averaging techniques. Digital quantification of enzymes typically involves the observation and counting of individual molecules segregated intoRead More…
Transwell Integrated Organoid Chip Simulates Tumor Metastasis
Tumor heterogeneity long been recognized as a significant barrier to advancing personalized diagnosis and treatment. Among its manifestations, tumor metastasis stands out as a common and serious feature of malignant tumors, profoundlyRead More…
5-Minute Ultrafast PCR Based on Digital Microfluidics
Background PCR is widely regarded as the gold standard for nucleic acid testing (NAAT) due to its excellent sensitivity, tolerance to nucleotide variations, and ability to perform multiplex detection. The development ofRead More…
Programmable Self-Driven Technology Empowers Multiplex Point-of-Care Immunoassays
In recent years, global public health crises have become increasingly prevalent, necessitating the development of efficient platforms for rapid detection and control their spread. However, traditional diagnostic approaches often involve intricate andRead More…