Poly (lactic-co-glycolic acid) (PLGA) has become a front-runner in the development of modern drug delivery systems (DDSs) due to its remarkable biocompatibility, biodegradability, and FDA approval for human use. Despite its popularity,Read More…
Advancing Biomedical Innovation: Microfluidic Chip Development for Organ-on-a-Chip Models
Introduction: The Emergence of Organ-on-a-Chip Technologies Researchers experienced an increased need for physiologically relevant in vitro models because traditional 2D cell cultures proved insufficient and animal models presented ethical and predictive challenges.Read More…
Microfluidics-Enabled Cell Separation and Sorting: Transforming Precision Research and Therapeutics
Introduction: The Evolution of Cell Separation and Sorting The development of cell separation and sorting technologies remains essential for advancements in modern biology along with biotechnological developments and medical science. The selectiveRead More…
How Microfluidics is Reshaping the Future of Cell Therapy
In recent years, adoptive cell therapy (ACT) has demonstrated immense potential in cancer treatment. The remarkable efficacy of CAR-T cells in leukemia therapy is well recognized. Meanwhile, the FDA’s approval of twoRead More…
UDA-Seq: Universal Droplet Microfluidics-Based Combinatorial Indexing
Recently, scientists published a research paper titled “UDA-seq: universal droplet microfluidics-based combinatorial indexing for massive-scale multimodal single-cell sequencing” in Nature Methods. The research team independently developed a novel single-cell multi-omics sequencing technologyRead More…
Sensitive Phenotyping of Serum Extracellular Vesicles on a SERS-Microfluidic Platform for Early-Stage Clinical Diagnosis of Ovarian Carcinoma
Extracellular vesicles (EVs) hold tremendous potential as liquid biopsy biomarkers for cancer diagnosis. Ovarian cancer (OvCa), with its high mortality rate and lack of effective early diagnostic methods, poses a severe threatRead More…
Comparative Study on Microfluidic Chip Manufacturing Technologies
Microfluidic technology has advanced significantly over the past few decades, becoming an irreplaceable part of complex tools in healthcare, environmental monitoring, and chemical engineering. Microfluidic chips, at the heart of this transformativeRead More…
SERS-Based Droplet Microfluidic Chip for Highly Sensitive and High-Throughput Detection of Cancer Exosomes
Exosomes are nanoscale extracellular vesicles that carry a variety of biomolecules and play an important role in physiological and pathological processes. Their characteristics make them ideal biomarkers for cancer diagnosis. Studies haveRead More…
A Multifunctional Anisotropic Myocardial Patch Based on Microfluidic Technology Promotes Myocardial Infarction Recovery
Myocardial infarction (MI) is a life-threatening condition caused by the sudden blockage of coronary arteries, often accompanied by serious consequences such as abnormal electrical signal conduction, ventricular remodeling, and fibrosis. Although traditionalRead More…
Wearable Analyzer Integrating Microneedle and Electrochemical Sensors for In Vivo Monitoring of Glucose and Lactate
Background Continuous monitoring of clinically relevant biomarkers in interstitial fluid (ISF) using microneedle (MN)-based assays has the potential to transform healthcare. Researchers from McMaster University have proposed an integrated system, called theRead More…