Droplet-based microfluidics has moved far beyond a clever way to generate emulsions. It is rapidly becoming a core technology for single-cell analysis, high-throughput screening, and functional tissue models. At the heart of thisRead More…
Microfluidics technology emerged in the early 1990s from research on microfluidic manipulation using micro-electro-mechanical system (MEMS). Over the past decades, advancements in analytical chemistry and life sciences have expanded the applications of microfluidic chip systems to nanofiber synthesis,Read More…
In the era of big biology, understanding individual cells—one by one—has become the holy grail of precision medicine, disease modeling, and synthetic biology. At the heart of this revolution lies single-cell phenomics:Read More…
This article provides a comprehensive overview of the progress made in the application of droplet microfluidics to single-cell analysis. The development of droplet microfluidics and its key features as a single-cell toolRead More…
Poly (lactic-co-glycolic acid) (PLGA) has become a front-runner in the development of modern drug delivery systems (DDSs) due to its remarkable biocompatibility, biodegradability, and FDA approval for human use. Despite its popularity,Read More…
Introduction: The Emergence of Organ-on-a-Chip Technologies Researchers experienced an increased need for physiologically relevant in vitro models because traditional 2D cell cultures proved insufficient and animal models presented ethical and predictive challenges.Read More…
Introduction: The Evolution of Cell Separation and Sorting The development of cell separation and sorting technologies remains essential for advancements in modern biology along with biotechnological developments and medical science. The selectiveRead More…
In recent years, adoptive cell therapy (ACT) has demonstrated immense potential in cancer treatment. The remarkable efficacy of CAR-T cells in leukemia therapy is well recognized. Meanwhile, the FDA’s approval of twoRead More…
Recently, scientists published a research paper titled “UDA-seq: universal droplet microfluidics-based combinatorial indexing for massive-scale multimodal single-cell sequencing” in Nature Methods. The research team independently developed a novel single-cell multi-omics sequencing technologyRead More…
Extracellular vesicles (EVs) hold tremendous potential as liquid biopsy biomarkers for cancer diagnosis. Ovarian cancer (OvCa), with its high mortality rate and lack of effective early diagnostic methods, poses a severe threatRead More…